Unit 4: Cell Communication and Cell Signaling


This is the Unit -4 section of CSIR NET Life Sciences examination syllabus. Unit name is Cell Communication and Cell Signaling. In this unit, Advanced  Cell biology and Immunology topic are included.
Cell Communication and Cell Signaling
Unit 4 Syllabus
  • Host-parasite interaction: Recognition and entry processes of different pathogens like bacteria, viruses into animal and plant host cells, alteration of host cell behavior by pathogens, virus-induced cell transformation, pathogen-induced diseases in animals and plants, cell-cell fusion in both normal and abnormal cells. 
  • Cell signaling: Hormones and their receptors,  cell surface receptor, signaling through G-protein coupled receptors, signal transduction pathways, second messengers, regulation of signaling pathways, bacterial and plant two-component signaling systems, bacterial chemotaxis, and quorum sensing. 
  • Cellular communication: Regulation of hematopoiesis, general principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix,  integrins, neurotransmission and its regulation.
  • Cancer: Genetic rearrangements in progenitor cells, oncogenes, tumor suppressor genes, cancer and the cell cycle, virus-induced cancer, metastasis, interaction of cancer cells with normal cells, apoptosis, therapeutic interventions of uncontrolled cell growth.
  • Innate and adaptive immune system: Cells and molecules involved in innate and adaptive immunity, antigens, antigenicity, and immunogenicity. B and   T cell  epitopes,  structure and  function of antibody molecules, generation of antibody diversity, monoclonal antibodies, antibody engineering, antigen-antibody interactions, MHC molecules, antigen processing and presentation, activation and differentiation of B and T cells, B and T  cell receptors, humoral and cell-mediated immune responses, primary and secondary immune modulation, the complement system, Toll-like receptors, cell-mediated effector functions, inflammation, hypersensitivity and autoimmunity, immune response during bacterial (tuberculosis), parasitic (malaria) and viral (HIV) infections, congenital and acquired immunodeficiencies, vaccines. 

Unit – 4 Free Study materials:

Cells of Immune System

What are the Cells of Immune System? (Basic Immune Cells)

Lymphocytes are the central cells of immune system, responsible for acquired immunity & the immunologic attributes of diversity, specificity, many and self/non-self recognition. It constitutes 20% to 40% of the body’s WBC and 99% of the cells in the lymph. The lymphocytes can be broadly subdivided into three populations – B-cells, T-cells, Null cells-on the […]