What is the basic bioSynthesis of Deoxyribonucleotides?

synthesis of Deoxyribonucleotides

The normal cell consists of 5 to 10 times as much RNA (mRNAs, rRNAs and also tRNAs) as DNA. For that reason, most of the nucleotide biosynthesis has as its objective the manufacturing of rNTPs. Nonetheless, since multiplying cells should reproduce their genomes, the manufacturing of dNTPs is likewise needed. …

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Clinical Significances of Purine Metabolism

Clinical Significances of Purine Metabolism

Clinical problems associated with nucleotide metabolism in humans are predominantly the result of abnormal catabolism of the purines. Follow this point on the Clinical Significances of Purine Metabolism. The clinical consequences of abnormal purine metabolism range from mild to severe and even fatal disorders. Clinical manifestations of abnormal purine catabolism …

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Nucleic Acid Stability : Stabilization in biological systems

Nucleic Acid Stability : Stabilization in biological systems

Nucleic acid structures are stabilized by non-covalent intramolecular interactions between the bases. All biological processes involving DNA and RNA require these structures to be in the stable and in the appropriate conformation. It is important to know how nucleic acids form their biologically active states and how these active states …

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