What is Fidelity of DNA Replication in Normal?

fidelity of DNA Replication in normal

DNA replication is, by far, the most accurate of known enzyme-catalyzed processes. The error rate per base pair per round of replication is about 10-9 to 10-10. The accuracy cannot be explained, however, by the different binding energies between correct and incorrect base pairs (this amounts to only a 100 …

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What are the Basics of pH concept and its Importance?

ph concept basics

The nature of the solution (acidic, alkaline (or) neutral) can be represented in terms of either hydrogen ion concentration (or) hydroxyl ion concentration. This naturally explains the pH concept. In 1909, Sorenson used a logarithmic scale for expressing the H+ concentration. This scale was called “pH”, Where “P” stands for …

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What are the importance of Coupling Reactions in Biological Systems?

coupling reactions

What is a coupling reaction? Before going to discuss this, we need to know about Energy. Energy is the capacity to do work and appears in many different inter-convertible forms: light, heat, electrical, mechanical, and so on. Energy can be kinetic (‘active’) or potential (‘stored’). The water behind a dam …

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Bioenergetics: Study of Free Energy Transformation and its changes

bioenergetics - energy transformation

Thermodynamics is the branch of physical chemistry that deals with energy changes and Biochemical thermodynamics (or biochemical energetics of bioenergetics as it is also called) is the field of biochemistry concerned with the energy transformation and use of energy by living cells (Energy transformation). The chemical reactions occurring in living beings (or biochemical reactions) …

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Hydrophobic Interactions in Proteins Structure – Basics and Structure

hydrophobic interactions in proteins

Hydrophobic interactions in proteins Structure describe the relations between water and hydrophobes (low water-soluble molecules). Hydrophobes are nonpolar molecules and usually have a long chain of carbons that do not interact with water molecules. The mixing of fat and water is a good example of this particular interaction. The common …

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